Brutal Strength
Pop Goes the Weasel
Eruption
Scourge Hook: Pain Resonance
Add-ons
Unicorn Medallion
Lab Photo
Highest-winning Wesker build (70% kill rate). Brutal Strength breaks quickly with the dash, and three perks handle regression.

Difficulty: Intermediate · Patch 10.2.2, data from October 28, 2026.
Albert Wesker is a brilliant and ruthless mastermind infused with the power of Uroboros.

Virulent Bound: 2 tokens; a 0.5 s bound (about 7 m), chainable into a 1 s bound (about 14 m) at 14 m/s.
The Mastermind can barrel forward, Infecting Survivors with the Uroboros virus or leaping over obstacles.
Press and hold the Power button to charge a Bound attack. While charging, The Mastermind moves slightly slower as he prepares his strike. When charged, press the Attack button to Bound. If The Mastermind hits a Survivor, that Survivor becomes Infected (or furthers their Infection). Should The Mastermind crash into something during this Bound, he will slam the Survivor, causing damage; if not, the Survivor is thrown, losing a health state if they are thrown into any solid object.
If Virulent Bound hits a window or dropped pallet, The Mastermind will special-vault the obstacle.
SPECIAL EFFECT: UROBOROS INFECTION
Upon being hit by Virulent Bound, Survivors become Infected. Infected builds over time, and when fully Infected, the Survivor suffers from a 4% Hindered status effect. If a Virulent Bound grabs and slams a Survivor while they are fully Infected, The Mastermind will automatically carry them.
SPECIAL INTERACTION: FIRST AID SPRAY
At the beginning of each trial, several Supply Crates spawn. Each contains a First Aid Spray. When Infected, a Survivor can use the First Aid Spray on themselves or another, removing the Infection. Each First Aid Spray has a set number of charges. After using a First Aid Spray, the Survivor's location is briefly revealed by Killer Instinct.
Add-ons
Unicorn Medallion
Lab Photo
Highest-winning Wesker build (70% kill rate). Brutal Strength breaks quickly with the dash, and three perks handle regression.
Add-ons
Unicorn Medallion
Lab Photo
Generic build: more info (BBQ) and a safer start (CI).
Add-ons
Uroboros Tendril
Leather Gloves
General / Trapper perks plus Wesker's Awakened Awareness: easy to play.
"Gen-Kick Based Build" variant: a different playstyle from the standard build, to vary your matches.